脳科学を超えた新しい学問分野を創設する

Achievements

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2015

Publications

  • Koganezawa N, Gisetstad R, Husby E, Doan TP, Witter MP. Excitatory postrhinal projections to principal cells in the medial entorhinal cortex. J. Neurosci.  in press

  • Shirao T and Koganezawa N, “The role of drebrin-binding stable actin filaments in dendritic spine morphogenesis” in The cytoskeleton in Health and Disease, Schatten H eds. Springer, pp.363-372 (2015)
  • Ohara Y, Koganezawa N, Yamazaki H, Roppongi R T, Sato K, Sekino Y, Shirao T, “Early-stage development of human-induced pluripotent stem cell (hiPSC)-derived neurons” J. Neurosci. Res. 93:1804-13 (2015)Down Load (free)
  • Shioda N, Sawai M, Ishizuka Y, Shirao T., Fukunaga K. “Nuclear translocation of calcium/calmodulin-dependent protein kinase IIδ3 promoted by protein phosphatase-1 enhances brain-derived neurotrophic factor expression in dopaminergic neurons.” J. Biol. Chem. J.  290: 21663-21675 (2015)

  • Shimizu H, Ishizuka Y, Yamazaki H, Shirao T. "Allopregnanolone increases mature excitatory synapses along dendrites via protein kinase A signaling." Neuroscience  305:139-45 (2015)

  • Fujieda T, Koganezawa N, Ide Y, Shirao T and Sekino Y. “An Inhibitory Pathway Controlling the Gating Mechanism of the Mouse Lateral Amygdala Revealed by Voltage-Sensitive Dye Imaging.” Neuroscience Letters 590:126-131 (2015)
  • Xu S-Q, Buraschi S, Morcavallo A, Genua M, Shirao T, Peiper SC, Gomella LG, Birbe R, Belfiore A, Iozzo RV, Morrione A “A novel role for drebrin in regulating progranulin bioactivity in bladder cancer.” Oncotarget  6:10825-10839 (2015)

International Conference

  1. Society of Toxicology 54th Annual Meeting, 2015, Tomoaki Shirao, Noriko Koganezawa, Anggraeini Puspitasari, Yuko Sekino. “Acute radiotoxicity on fear memory and synaptic protein.” San Diego, USA, March 22-26.
  2. 25th ISN Biennial Meeting, 2015, Shirao T, “Myosin II dependent loss of Stable F-actin from dendritic spines by LTP induction” in the symposium “Novel Mechanism in Synaptic Plasticity”. Cairns, Australia, August 23-27, 2015.
  3. 25th ISN Biennial Meeting, 2015, Puspitasari A, Koganezawa N, Kajita Y, Shirao T, “Transient effect of X-irradiation and Carbon ion-irradiation on synaptic function.” Cairns, Australia, August 23-27, 2015.
  4. 25th ISN Biennial Meeting, 2015, Koganezawa N, Ohara Y, Yamazaki H, Roppongi R T, Sato K, Sekino Y,  Shirao T, “Slow axonal growth of human iPSCs-derived neurons.” Cairns, Australia, August 23-27, 2015.
  5. 25th ISN Biennial Meeting, 2015, Ishizuka Y, Shimizu H, Shirao T, “Histone deacetylase mediates drebrin loss from dendritic spines induced by amyloid beta oligomers” Cairns, Australia, August 23-27, 2015.
  6. 25th ISN Biennial Meeting, 2015, Kajita Y, Shirao T, “Drebrin knockout results in the impairment of olfaction and adult neurogenesis.” Cairns, Australia, August 23-27, 2015.
  7. 15th Annual Meeting of Safety Pharmacology Society Meeting, 2015 Shirao T, Ishizuka Y, Hanamura K, Koganezawa N, Ootsu M, Yamazaki H. “Differential effects of astemizole on the neurite growth and synaptogenesis of neurons.” Prague, Czech Republic, September 28- Oct 1
  8. Manitoba Neuroscience Network (MNS) Seminar, 2015 "Novel actin-dependent mechanism of synaptic plasticity", Winnipeg, MB, Canada, Oct 13
  9. 25th Neuropharmacology Conference, Synaptopathy-from biology to Therapy, 2015, Koganezawa N., Yamazaki H., Roppongi RT., Arayama Y., Shirao T, Ishizuka Y, Hanamura K, Tanaka N, Sekino Y. “Axonal growth of human iPSCs-derived neurons is slow.” Chicago IL, USA, Oct. 15-16.
  10. 25th Neuropharmacology Conference, Synaptopathy-from biology to Therapy, 2015, Shuchuan Miao, Noriko Koganezawa, Anggraeini Puspitasari, Takashi Hiruma, Kenji Hanamura, Reiko T. Roppongi, Tomoaki Shirao “X-irradiation-induced drebrin decrease indendritic spines associated with fear memory is mediated by NMDA receptor activity.”Chicago IL, USA, Oct. 15-16.
  11. 25th Neuropharmacology Conference, Synaptopathy-from biology to Therapy, 2015, Shirao T, Ishizuka Y, Hanamura K, Tanaka N, Sekino Y. “Inhibition of histone deacetylase activity protects the synaptopathy induced by amyloid beta oligomers.”Chicago IL, USA, Oct. 15-16.
  12. Society for Neuroscience 45th Annual Meeting, 2015, Hiroyuki Yamazaki, Tomoaki Shirao, “CaMKIIbeta is localized in dendritic spine in a drebrin-dependent and drebrin-independent manners” Chicago IL, USA, Oct. 17-21
  13. Society for Neuroscience 45th Annual Meeting, 2015, Shuchuan Miao, Noriko Koganezawa, Takashi Hiruma, Kenji Hanamura, Anggraeini Puspitasari, Reiko T. Roppongi, Tomoaki Shirao “X-irradiation-induced decrease in drebrin clusters within dendritic spines of cultured hippocampal neurons: Association with NMDA receptor and histone deacetylase activities.” Chicago IL, USA, Oct. 17-21
  14. Society for Neuroscience 45th Annual Meeting, 2015, Koganezawa, Y. Kajita, H. Yasuda, K. Sakimura, T. Shirao; “Primary cultured hippocampal neurons prepared from drebrin knockout mice show the less immunoreactivity of MAP2” Chicago IL, USA, Oct. 17-21

Domestic Conference

not available

Achievements

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